Testosterone Deficiency OVERVIEW
There are two types of Hypogonadism. Hypergonadotropic, (Primary) and Hypogonadotropic (Secondary).
Primary Hypogonadism is associated with testicular, or ovarian failure.1 7 Men are more likely to be born with the condition 99,131,136,172 than women. However, in both sexes, numbers increase dramatically by middle age.1, 2, 89. In men, there is increasing evidence that Testicular Dysgenesis Syndrome172, is responsible in large part for the increase, as Testicular malformation progressively takes effect.
As a baby grows and becomes adult, disruptive factors some into play. Certain surgical procedures, Cancer, Childhood Leukemia, Juvenile Rheumatoid Arthritis, Mumps (Orchitis), serious injury,22 or burns, pubertal malfunction, chronic diseases,1328 toxic exposure,94 acute anaemia, HIV AIDS,51 Orchitis, Testicular90, or Ovarian43 disease, prescribed drugs and cancer treatments, amongst others, add significantly to the overall number of people living in an undetected, treatable, state.
Detecting post-pubertal primary Hypogonadism is difficult to do, because physical symptoms subtly occur over time. Sufferers tend to initially experience anti-social behavioural effects such as mood swings, loss of libido anger, and depression as the condition begins to take effect. However, most physicians do not associate these symptoms with the condition.
Secondary Hypogonadism is associated with Pituitary problems and are quite rare at birth.
After birth, problems with the pituitary may be associated with serious illnesses, HIV AIDS, malnutrition, pituitary tumours, medications, Hematochromosis and pituitary insufficiency. Secondary Hypogonadism occurs more often in women than in men.
Treatments for Hypogonadism differ according to source and age. In adult patients, who acquire Primary Hypogonadism, Testosterone is the recommended therapy. However, there are many issues to consider before prescribing. Secondary Hypogonadism often attracts stimulation by another hormone in an attempt to elicit better production from the testicles.
In childhood, treatments depend on the particular problem discovered and the age at discovery.
The problem all Hypogonadal people face is one of detection. A continued reluctance to test for Hypogonadism must be reversed in order to allow Hypogonadal people to come out from "behind the eight ball" and enjoy a level playing field.
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Opinion. The publication of the new guidelines highlights the Hypogonadism problem for many millions across the world. The impact of Hypogonadism on a patient's life varies, but is never positive. Irrespective of how the patient feels at diagnosis, the failure to treat the condition ensures endocrine imbalance, to the ultimate detriment of the patient.
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